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Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013.

How Avanafil works?

Avanafil works by relaxing muscles in the penis. This increases blood flow into the penis, allowing more blood to enter when you are sexually aroused.

Avanafil is a PDE5 inhibitor. PDE5 is an enzyme found in certain body tissues, including the penis. When sexual stimulation occurs, nitric oxide is released into the penis, and this triggers a chemical called cyclic guanosine monophosphate (cGMP). cGMP relaxes and widens blood vessels in the penis, allowing more blood to enter. Avanafil inhibits PDE5, preventing it from breaking down cGMP so that blood vessels can stay open and blood flow can continue.

Avanafil has been shown to be effective in treating erectile dysfunction in men of all ages and has been shown to increase erections and improve sexual performance in men with erectile dysfunction due to various causes, including diabetes and prostate surgery.

What Avanafil used for?

Avanafil is used to treat erectile dysfunction (impotence).

How should i take avanafil?

Avanafil can be taken with or without food. Take exactly as prescribed by your doctor.

Follow the directions on your prescription label.

Avanafil is usually taken 30 minutes before sexual activity. You may take it up to 4 hours before sex. Do not take Avanafil more than once per 24 hours. Contact your doctor or seek emergency medical attention if you have sudden vision loss.

A high-fat meal (such as a cheeseburger and french fries) may delay how quickly the drug begins working.

Avoid drinking alcohol, which can increase some of the side effects of Avanafil.

Dosages and brands

Avanafil is available in 50, 100, and 200 mg dosages. The brand names are Avana, Top Avana, Super Avana, Extra Super Avana, Stendra and Spedra.


Avanafil should not be taken with nitrates or nitroglycerin because it can cause a sudden drop in blood pressure.

You should also avoid taking Avanafil if you have a history of heart attack or stroke.

Side effects

If you are allergic to avanafil or any other ingredient of this medicine, do not take it.

Common side effects include headaches and heartburn, as well as flushed skin. Avanafil may also cause nasal congestion.

Do not take avanafil if you are taking nitrate medicines, such as isosorbide dinitrate, isosorbide mononitrate, nitroglycerin or amyl nitrite.


Avanafil tablet is manufactured by Sunrise Remedies Pvt. Ltd in India.